The aim is to identify and optimize new anticancer agents targeting pancreatic and breast cancers.
Conducted molecular docking studies to evaluate compound interactions.
Performed ADME (Absorption, Distribution, Metabolism, Excretion) analysis to predict pharmacokinetic properties.
Synthesized new hydropyrimidine linked amide-pyridine derivatives.
Identified 6m as a promising lead compound for anticancer activity.
Results indicate potential effectiveness against pancreatic and breast cancers.
Abstract
This study ascertains 6m as a promising lead for further biological evaluation and structural optimization toward the development of potential anticancer agents against pancreatic and breast cancers.