What does this research mean for the field?

White coat hypertension is highly prevalent, affecting nearly two-thirds of chronic kidney disease patients with elevated clinic blood pressure, and is significantly associated with comorbid diabetes. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to compare home and clinic blood pressure readings in patients with chronic kidney disease to detect white coat hypertension.

April 4, 2026Open Access

Comparison between home and clinic blood pressure measurement in hypertensive chronic kidney disease patients

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Key Result

White coat hypertension affected 65.2% of chronic kidney disease patients with uncontrolled clinic blood pressure and was significantly associated with diabetes (OR 4.92).

Key Points

The aim is to compare home and clinic blood pressure readings in patients with chronic kidney disease to detect white coat hypertension.
Cross-sectional study design
Involvement of 66 chronic kidney disease patients
Comparison of home and clinic blood pressure readings
Assessment of white coat hypertension prevalence
Mean clinic systolic blood pressure was significantly higher than home systolic blood pressure
65.2% of patients had white coat hypertension
White coat hypertension was significantly associated with diabetes (odds ratio: 4.92)

Structured PICO

Does home blood pressure measurement compared to clinic measurement improve the detection of white coat hypertension in CKD patients with uncontrolled clinic BP?

Population

Chronic kidney disease (CKD) patients with uncontrolled clinic blood pressure (BP)

Intervention

Home blood pressure measurement

Comparator

Clinic blood pressure measurement

Outcome

Difference between home and clinic BP readings and detection of white coat hypertension (WCH)surrogate

White coat hypertension is highly prevalent (65.2%) in CKD patients with elevated clinic BP, highlighting the need for routine home BP monitoring for accurate diagnosis.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Background Hypertension is common in chronic kidney disease (CKD), and white coat hypertension (WCH) complicates its diagnosis and treatment. Patients and methods We conducted a cross-sectional study of 66 CKD patients with uncontrolled clinic blood pressure (BP) at the nephrology outpatient clinic at Suez Canal University Hospital, comparing home and clinic BP readings to detect WCH. Results The mean clinic systolic BP (167.2 ± 13.7 mmHg) was significantly higher than the mean home systolic BP (131 ± 12.5 mmHg) ( P <0.005). WCH was identified in 65.2% of patients and was significantly associated with diabetes (odds ratio: 4.92; 95% confidence interval: 1.34–18.15). Conclusions WCH is highly prevalent, affecting nearly two-thirds of CKD patients with elevated clinic BP, highlighting the need for routine home BP monitoring for accurate diagnosis and individualized management.

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Discussion

Authors

Mohammed Abdel Gawad

D Z Abdel Hamid

Wallaa Y. Badr-Aldin

Journals

Journal of The Egyptian Society of Nephrology and Transplantation

Actions

Institutions

Cairo University

Alexandria University

Suez Canal University

References and Citations

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Comparison between home and clinic blood pressure measurement in hypertensive chronic kidney disease patients

Key Result

Key Points

Structured PICO

Main Result

Abstract

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Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

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Discussion

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