Differences in Clinical Manifestations and Islet Autoantibodies by Age in Adult-Onset Type 1 Diabetes | Synapse
April 4, 2026
Differences in Clinical Manifestations and Islet Autoantibodies by Age in Adult-Onset Type 1 Diabetes
Key Points
To examine the variations in clinical manifestations and islet autoantibody profiles in adult-onset type 1 diabetes based on age.
Analyzed clinical data of adult-onset type 1 diabetes patients
Measured frequency of diabetic ketoacidosis (DKA) incidents
Assessed total islet autoantibody levels
Observed reduced frequency of DKA in adult-onset type 1 diabetes patients
Detected fewer total islet autoantibodies compared to childhood-onset cases
Abstract
Adult-onset type 1 diabetes is characterized by a reduced frequency of DKA and by fewer total islet autoantibodies. Our findings can help in the accurate diagnosis of type 1 diabetes in adults.