Examining pre-analytical factors for bioanalysis of protein therapeutics crossing the blood–brain barrier through receptor-mediated transcytosis | Synapse
The aim is to investigate the influence of pre-analytical factors on the bioanalysis of protein therapeutics that cross the blood-brain barrier.
Examine various pre-analytical procedures
Assess their impact on bioanalysis outcomes
Develop optimized workflow for screening
Highlighted significant effects of pre-analytical factors on bioanalysis
Identified specific procedures that could improve efficiency
Facilitated the development of a more streamlined testing process
Abstract
Careful investigation of these pre-analytical procedures should be conducted to understand their impact. This will facilitate the development of an optimized and efficient workflow for discovery screening.