What question did this study set out to answer?

To investigate healthcare resource utilization (HCRU) and costs associated with disease progression following first-line systemic therapy in advanced endometrial cancer.

April 5, 2026Value in Health Regional Issues0 citationsOpen Access

Healthcare Resource Utilization and Costs After Disease Progression With First-Line Systemic Therapy in Patients With Advanced Endometrial Cancer in the United States

LMLaura Moore-Schiltz SLSolomon J. Lubinga JTJoseph Tkacz

Key Points

To investigate healthcare resource utilization (HCRU) and costs associated with disease progression following first-line systemic therapy in advanced endometrial cancer.
Analyzed healthcare resource utilization data post-treatment initiation
Assessed treatment-free interval (TFI) less than 6 months
Evaluated costs related to disease progression and treatment plans
Identified higher healthcare resource utilization correlated with shorter treatment-free intervals
Found significant increase in endometrial cancer-specific costs following disease progression
Suggested that effective upfront treatments can reduce subsequent healthcare costs

Abstract

Patients with advanced EC initiating subsequent treatment face considerable HCRU and costs. Because most patients had a <6-month TFI, which is indicative of faster disease progression and associated with numerically higher HCRU and significantly higher EC-specific costs, this study suggests that effective up-front treatments may help alleviate this burden.

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Cite This Study

Moore-Schiltz et al. (Wed,) studied this question.

synapsesocial.com/papers/69d1fc28a79560c99a0a1cb4 https://doi.org/https://doi.org/10.1016/j.vhri.2026.101618

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