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April 5, 2026

Prevalence of Sarcopenia in Children Undergoing Total Pancreatectomy with Islet Autotransplantation (TPIAT) and Implications for Short-Term Surgical Outcomes

Key Points

To evaluate the prevalence of sarcopenia in children undergoing total pancreatectomy with islet autotransplantation and its implications for surgical outcomes.
Assessment of sarcopenia using psoas muscle and total abdominal skeletal muscle measurements.
Analysis of 30-day postoperative outcomes.
Comparison of pre-operative pain levels with incidence of sarcopenia.
Sarcopenia prevalence was found to be 32.4% by psoas muscle measurement.
Total abdominal skeletal muscle measurement showed lower prevalence of sarcopenia.
No association was found between sarcopenia and postoperative outcomes in the first 30 days.
Higher frequency of pre-operative pain was positively associated with sarcopenia.

Abstract

Sarcopenia was 32.4% prevalent by psoas muscle measurement but was less prevalent by total abdominal skeletal muscle measurement in children undergoing TPIAT. There was no relationship between the presence of sarcopenia or decreasing muscle mass and 30-day postoperative outcomes but there was a positive association between higher frequency of pre-operative pain and sarcopenia.

Prevalence of Sarcopenia in Children Undergoing Total Pancreatectomy with Islet Autotransplantation (TPIAT) and Implications for Short-Term Surgical Outcomes

Key Points

Abstract

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