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April 5, 2026Open Access

m1A modification of tRNA in anaplastic thyroid cancer

Key Points

This research investigates how m1A modification of tRNA affects the progression of anaplastic thyroid cancer and its underlying molecular mechanisms.
Utilized human anaplastic thyroid cancer cells KHM-5M for experimentation.
Examined the impact of TRMT6/TRMT61A on tRNA modification and cancer progression.
Identified significant effects of m1A modification on cancer cell behavior.
Revealed potential connections between tRNA modifications and cancer molecular pathways.

Abstract

This project aims to explore the impact of TRMT6/TRMT61A-mediated m1A modification of tRNA on the progression of anaplastic thyroid cancer and its molecular mechanism. The cells used in this study are human anaplastic thyroid cancer cells KHM-5M.

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Cite This Study

丁颖(Ying Ding) (Thu,) studied this question.

synapsesocial.com/papers/69d1fd4ea79560c99a0a34cc https://doi.org/https://doi.org/10.26036/cnp0008154

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m1A modification of tRNA in anaplastic thyroid cancer | Synapse