What question did this study set out to answer?

Investigate whether menstruation acts as a trigger for familial Mediterranean fever attacks or if symptoms resemble premenstrual discomfort.

April 6, 2026Lara D. Veeken0 citations

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Menstruation in adolescents with Familial Mediterranean Fever: attack trigger or dysmenorrhea? A prospective cross-sectional study

FKFeray Kaya EKElif Kucuk LKLütfiye Koru

Key Points

Investigate whether menstruation acts as a trigger for familial Mediterranean fever attacks or if symptoms resemble premenstrual discomfort.
Conducted a prospective cross-sectional study with adolescent participants.
Assessed symptom patterns during menstruation in relation to FMF attacks.
Menstruation does not uniformly trigger FMF attacks in all adolescents.
Some symptoms reported are linked to premenstrual syndrome or similar conditions.

Abstract

Our findings raise the possibility that menstruation does not uniformly act as a trigger for FMF attacks and that a subset of symptoms reported during the menstrual period may reflect premenstrual discomfort or PMS/PMDD-like features rather than true FMF attacks.

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Menstruation in adolescents with Familial Mediterranean Fever: attack trigger or dysmenorrhea? A prospective cross-sectional study

Key Points

Abstract

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