The role of olfactory and salivary gland pathways in periodontal disease-mediated Alzheimer’s disease progression: mechanistic insights and early diagnostic implications

Key Points

• This research aims to understand how periodontal disease impacts the progression of Alzheimer’s disease through specific pathways.
• Examined the relationship between periodontal disease and neuroinflammation.
• Investigated the roles of olfactory and salivary gland pathways.
• Considered early diagnostic indicators linked to Alzheimer’s susceptibility.
• Periodontal disease was found to contribute significantly to neuroinflammation related to Alzheimer’s.
• Olfactory dysfunction and salivary gland hypofunction are emerging as early diagnostic indicators for Alzheimer’s risk.