Subclinical atherosclerosis was found in 14% of spondylosis patients, and carotid intima-media thickness significantly correlated with lumbar (r=0.41) and cervical (r=0.32) spondylosis severity.
Is spondylosis severity associated with subclinical atherosclerosis measured by carotid intima-media thickness?
Severe lumbar and cervical spondylosis is associated with a higher prevalence of subclinical atherosclerosis as measured by carotid intima-media thickness.
Absolute Event Rate: 0% vs 0%
Background and aim Previous studies have established an association between peripheral osteoarthritis and subclinical atherosclerosis; however, the relationship with spondylosis remains insufficiently explored. The objective of this study was to evaluate the link between spondylosis and subclinical atherosclerosis and to examine the possibility of a causal relationship. Patients and methods A cross-sectional study was conducted, enrolled 100 patients with lumbar and/or cervical spondylosis presenting with low back and/or cervical pain. Radiographic evaluation included anteroposterior and lateral views, with spondylosis graded using the Lane index for lumbar and the Kellgren index for cervical involvement. Subclinical atherosclerosis was evaluated through the measurement of carotid intima-media thickness (CIMT) using Doppler ultrasonography. To evaluate the association between spondylosis severity and subclinical atherosclerosis, correlation and regression analyses were applied. Results Subclinical atherosclerosis was identified in 14% of patients. CIMT showed significant correlations with age, cervical pain severity, and the Lane index for lumbar spondylosis ( r =0.72, r =0.34, r =0.41; P <0.001). Additional significant correlations were found between CIMT and triglyceride levels, Roland–Morris disability score, and the Kellgren index for cervical spondylosis ( r =0.25, r =0.23, r =0.32; P =0.014). Conclusion Severe spondylosis was associated with a higher prevalence of subclinical atherosclerosis, suggesting a potential causal relationship. Validation of these findings requires larger, multicenter studies.
Hasan et al. (Thu,) reported a other. Subclinical atherosclerosis was found in 14% of spondylosis patients, and carotid intima-media thickness significantly correlated with lumbar (r=0.41) and cervical (r=0.32) spondylosis severity.