A 50 mL dose of 8.4% sodium bicarbonate more frequently achieved guideline-recommended serum sodium goals compared to 100 mL of 3% sodium chloride in severe hyponatremia.
Does a single 50 mL dose of 8.4% sodium bicarbonate improve obtainment of guideline-recommended post-intervention serum sodium goal concentrations compared to a 100 mL dose of 3% sodium chloride in patients with severe hyponatremia?
A single 50 mL dose of 8.4% sodium bicarbonate may be more effective than a 100 mL dose of 3% sodium chloride for achieving target serum sodium levels in severe hyponatremia.
Absolute Event Rate: 0% vs 0%
This study found that a single 50 mL dose of HTB more often resulted in obtainment of guideline-recommended post-intervention serum sodium goal concentrations than a 100 mL HTS dose. Additional studies are needed to confirm these findings and provide a more comprehensive assessment of safety and efficacy outcomes.
Ibarra et al. (Wed,) reported a other. A 50 mL dose of 8.4% sodium bicarbonate more frequently achieved guideline-recommended serum sodium goals compared to 100 mL of 3% sodium chloride in severe hyponatremia.
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