Aryl-Cyclohexanone as a Potential CB2 Agonist: In Vitro and In Silico Evidence in Inflammatory Modulation

Key Points

• This study aims to explore the anti-inflammatory effects of aryl-cyclohexanone through CB2 receptor activation.
• Utilized in vitro assays to assess the anti-inflammatory properties of aryl-cyclohexanone.
• Employed in silico analyses to predict interactions with CB2 receptors.
• Aryl-cyclohexanone demonstrated significant anti-inflammatory effects.
• Activation of CB2 receptors was confirmed as a mechanism behind its immunomodulatory action.