What question did this study set out to answer?

This research aims to compare the effectiveness of endovascular coil embolization and surgical ligation of the uterine artery in inducing uteroplacental insufficiency (UPI) in a preeclampsia model.

April 10, 2026Open Access

Endovascular coil embolization compared to surgical ligation of the uterine artery in a non-human primate model in a model of preeclampsia

Key Points

This research aims to compare the effectiveness of endovascular coil embolization and surgical ligation of the uterine artery in inducing uteroplacental insufficiency (UPI) in a preeclampsia model.
Used a non-human primate model of preeclampsia
Compared endovascular embolization with surgical ligation of the uterine artery
Assessed the efficacy of both techniques for inducing UPI
No statistically significant difference found between the two techniques
Endovascular embolization may be preferred due to its less invasive nature

Abstract

No statistically significant difference was found between the two methods, coils for endovascular embolization and surgical UPI. However, since endovascular embolization is a less invasive technique compared to ligation it may be preferred for induction of UPI in the NHP model.

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Discussion

Authors

A. Makris

Neelam Roshan

Jim Iliopoulos

Journals

Laboratory Animal Research

Actions

Institutions

The University of Sydney

Cedars-Sinai Medical Center

Western Sydney University

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Endovascular coil embolization compared to surgical ligation of the uterine artery in a non-human primate model in a model of preeclampsia

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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