What question did this study set out to answer?

To explore the association between alpha-gal syndrome and anaphylactic reactions to group B blood transfusions in non-B recipients.

April 10, 2026

Anaphylactic transfusion reaction to group B platelets related to alpha‐gal syndrome: A case report

Key Points

To explore the association between alpha-gal syndrome and anaphylactic reactions to group B blood transfusions in non-B recipients.
Clinical case report detailing patient history and reactions.
Laboratory evaluation for AGS antibodies in non-B individuals with tick exposure.
Assessment of allergic reactions to group B blood products.
Identification of anaphylactic transfusion reaction following administration of group B platelets.
Recommendation for AGS antibody screening in non-B patients with related allergic histories.
Advocacy for avoidance of group B transfusions in clinically suspected AGS cases.

Abstract

This case demonstrates a possible clinical association between AGS and anaphylactic transfusion reaction to group B blood products in non-B recipients. Early laboratory workups for AGS antibodies are recommended in non-B patients with a history of tick exposure and severe allergic reactions to meat consumption or transfusion of group B blood products. Meanwhile, transfusion of group B blood products should be avoided once AGS is suspected clinically in non-B patients.

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Authors

Oscar Andre Hinojosa

Amitava Dasgupta

Zhan Ye

Journals

Transfusion

Actions

Institutions

University of Kansas Medical Center

University of Missouri–Kansas City

References and Citations

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Building similarity graph...

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Anaphylactic transfusion reaction to group B platelets related to alpha‐gal syndrome: A case report

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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