The Novel HLA‐DRB1*16:80 Allele, Identified by Sanger Dideoxy Nucleotide Sequencing in a Chinese Individual

Key Points

• To identify and characterize the novel hla-drbi*16:80 allele in a Chinese individual through sequencing techniques.
• Used Sanger dideoxy nucleotide sequencing to analyze the genetic material.
• Focused on exon 4 to detect specific nucleotide changes.
• Compared findings with known hla-drbi alleles for identification.
• identified the hla-drbi*16:80 allele through a single nucleotide change.
• highlighted the genetic differences between hla-drbi*16:80 and hla-drbi*16:02:01:01.

Abstract