Functions of dendrobine in a zebrafish model of diabetic retinopathy

Key Points

• The central aim is to explore the therapeutic effects of dendrobine on diabetic retinopathy in a zebrafish model.
• Utilized a zebrafish model of diabetic retinopathy.
• Administered dendrobine to assess its effects on high-glucose conditions.
• Conducted morphological and transcriptomic analyses to evaluate outcomes.
• Dendrobine reduced high-glucose-induced damage in retinal structures.
• Morphological improvements were observed in treated zebrafish.
• Transcriptomic changes indicated positive responses related to therapeutic potential.

Abstract