This case report describes a rare presentation of orbital cellular myofibroma in a 30-year-old female who initially presented with right proptosis and conjunctival injection. Endovascular embolization followed by surgical resection revealed an unencapsulated, vascular tumor with histopathologic and molecular findings consistent with cellular myofibroma harboring an SRF::RELA gene fusion. This case highlights the diagnostic challenges associated with orbital tumors and the importance of considering myofibroma in the differential diagnosis. The report also underscores the role of multidisciplinary management in optimizing outcomes for patients with rare orbital neoplasms.
Anchouche et al. (Wed,) studied this question.