Successful propranolol therapy for infantile hepatic hemangioma with cardiac failure

Abstract Infantile hepatic hemangioma (IHH) can cause severe complications such as high‐output cardiac failure and growth faltering, requiring prompt diagnosis and intervention. In the absence of standardized treatment guidelines, propranolol has emerged as an effective and well‐tolerated therapy. We report a female infant with multifocal IHH who presented with high‐output cardiac failure, hepatomegaly, and growth faltering. She experienced rapid and sustained clinical as well as radiologic improvement with propranolol therapy. This case reinforces propranolol's role as a safe, effective first‐line therapy for symptomatic IHH and underscores the importance of early multidisciplinary care.