Perioperative management of Muckle-Wells syndrome necessitates careful intraoperative temperature monitoring and specific anesthesia planning to prevent cold-triggered inflammasome activation.
This case report highlights the perioperative and anesthetic management, particularly intraoperative temperature monitoring, for patients with cold-triggered cryopyrin-associated periodic syndromes.
Absolute Event Rate: 0% vs 0%
Cryopyrin-associated periodic syndrome (CAPS) is a rare family of autoinflammatory disorders characterized by constitutive inflammasome activation that can be triggered by exposure to cold temperatures. We discuss the case of a 49-year-old woman with Muckle-Wells syndrome, a subtype of CAPS, presenting for cervical lymph node biopsy to rule out lymphoma. The pathophysiology of CAPS, intraoperative temperature monitoring, and other anesthesia considerations are reviewed in this article.
Levin et al. (Wed,) reported a other. Perioperative management of Muckle-Wells syndrome necessitates careful intraoperative temperature monitoring and specific anesthesia planning to prevent cold-triggered inflammasome activation.