Evaluation of Selected Brain Damage Biomarkers in the Determination of Brain Damage in Dogs With Neurological Distemper

Key Points

• This research aims to determine the effectiveness of specific biomarkers in identifying brain damage in dogs suffering from neurological distemper.
• Measure serum concentrations of NSE, GFAP, CK-BB, IgG, and IgM
• Compare biomarker levels in dogs with neurological distemper vs. healthy controls
• Statistical analysis of biomarker levels to assess significance
• Serum levels of NSE, GFAP, and CK-BB were significantly elevated in affected dogs
• IgG and IgM levels were also increased but not as significantly as the three biomarkers
• Findings support the potential diagnostic role of NSE, GFAP, and CK-BB in brain damage assessment