Effects of a phenolic-rich grape pomace extract on intestinal barrier, gut microbiota, and adipose tissue in high-fat diet-fed mice.

Key Points

• This research aims to evaluate how grape pomace extract affects gut health and fat tissue in mice on a high-fat diet.
• Feeding high-fat diet to mice
• Administering phenolic-rich grape pomace extract
• Analyzing intestinal barrier integrity
• Examining gut microbiota composition
• Assessing changes in adipose tissue
• Improved intestinal barrier function observed
• Positive changes in gut microbiota diversity
• Decreased adipose tissue inflammation noted
• Lower endotoxemia levels detected