What question did this study set out to answer?

The aim is to evaluate interventions that prevent weight gain and metabolic issues in individuals experiencing first-episode psychosis with limited antipsychotic exposure.

April 12, 2026Open Access

Interventions to prevent antipsychotic-induced weight gain and metabolic complications in individuals with a first-episode psychosis and minimal antipsychotic exposure: a systematic review and meta-analysis

Key Points

The aim is to evaluate interventions that prevent weight gain and metabolic issues in individuals experiencing first-episode psychosis with limited antipsychotic exposure.
Conducted a systematic review and meta-analysis
Evaluated multidisciplinary team interventions
Focused on individuals with first-episode psychosis
Included studies investigating weight gain prevention
Multidisciplinary team interventions were found to be effective
Significantly reduced weight gain in individuals with first-episode psychosis
Recommended for implementation in treatment plans for patients

Abstract

Despite the importance of preventing weight gain in FEP, there have been few recent studies investigating this topic. Our results indicate that multidisciplinary team interventions are effective in preventing weight gain in FEP and should be offered to all patients.

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Interventions to prevent antipsychotic-induced weight gain and metabolic complications in individuals with a first-episode psychosis and minimal antipsychotic exposure: a systematic review and meta-analysis

Key Points

Abstract

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