Circulating histone H4 values can relate to disease severity in patients with alcoholic hepatitis and cirrhosis

Key Points

• The study aims to investigate the relationship between circulating histone H4 levels and disease severity in alcoholic hepatitis and cirrhosis.
• Measured circulating histone H4 levels in patients with alcoholic hepatitis and cirrhosis.
• Evaluated disease severity using clinical criteria and scoring systems.
• Higher levels of circulating histone H4 correlate with increased disease severity.
• Circulating histone H4 may serve as a potential biomarker for assessing alcoholic liver disease.