Interventions Targeting the Beef Feedlot Environment to Control Antimicrobial Resistance: A Mathematical Modelling Study

Key Points

• The research aims to understand how farm environments, particularly beef feedlots, contribute to antimicrobial resistance.
• Developed a mathematical model simulating conditions in beef feedlots.
• Analyzed the effects of environmental factors on bacterial persistence.
• Assessed the role of cleaning protocols and climate variables on bacterial resilience.
• The model indicates that antimicrobial resistant bacteria can thrive even without antimicrobial use.
• Stringent cleaning may not fully eliminate resistant bacteria under certain climate conditions.
• The feedlot environment shows significant resilience against interventions.

Abstract