What question did this study set out to answer?

The research aims to evaluate the safety and distribution of Au@Pt nanorods administered intraperitoneally in mice.

April 14, 2026

Toxicological assessment of intraperitoneal administration for Au nanorods with ultra-small Pt nanoparticles on surface (Au@pt NRs) in mice

AYAiyun YangCapital University TWTao WenChinese Academy of Medical Sciences & Peking Union Medical College JMJing MengChinese Academy of Medical Sciences & Peking Union Medical College

Key Points

The research aims to evaluate the safety and distribution of Au@Pt nanorods administered intraperitoneally in mice.
Administered Au@Pt NRs via different routes in mice
Observed distributions and histological changes
Conducted assessments of safety measures
Distributions and histological changes varied slightly between administration routes
Safety of Au@Pt NRs was confirmed as acceptable
Potential for biomedical applications via intraperitoneal route established

Abstract

In summary, Au@Pt NRs administered via different routes show slightly different distributions and histological changes, and their safety was acceptable, confirming their potential for biomedical applications via the intraperitoneal route.

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