What question did this study set out to answer?

The study aims to determine how preoperative CT-derived plaque characteristics relate to silent cerebral infarctions following total aortic arch replacement.

April 16, 2026Annals of Thoracic and Cardiovascular Surgery0 citationsOpen Access

CT-Derived Aortic Plaque Characteristics Predict MRI-Detected Silent Cerebral Infarction after Total Aortic Arch Replacement

FYFumio Yamana KSKazuo Shimamura TSTakayuki Shijo

Key Points

The study aims to determine how preoperative CT-derived plaque characteristics relate to silent cerebral infarctions following total aortic arch replacement.
Analyzed the incidence and distribution of silent cerebral infarctions after total aortic arch replacement.

Structured PICO

Do preoperative CT-derived aortic plaque characteristics predict MRI-detected silent cerebral infarction after total aortic arch replacement?

Population

Patients undergoing total aortic arch replacement (TAR)

Intervention

Preoperative computed tomography (CT) assessment of low-attenuation plaque (LAP, 0-60 HU) burden

Outcome

Incidence, distribution, and risk factors for new cerebral infarction lesions (NCILs) detected by MRI after total aortic arch replacementsurrogate

Preoperative CT-derived low-attenuation plaque burden is being investigated as a potential predictor for silent cerebral infarction following total aortic arch replacement.

Abstract

Purpose: Silent cerebral infarctions are common after aortic arch surgery; however, the predictive value of preoperative computed tomography (CT)-derived plaque characteristics remains unclear. We investigated the incidence, distribution, and risk factors for new cerebral infarction lesions (NCILs) after total aortic arch replacement (TAR), focusing on low-attenuation plaque (LAP, 0–60 Hounsfield units HU, a surrogate of lipid-rich vulnerable plaque) burden.

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