Evaluation of male reproductive function after aromatase inhibitor treatment during adolescence: case series with literature review

Key Points

• The central aim is to evaluate the impact of aromatase inhibitors on male reproductive function during adolescence.
• Case series design was utilized.
• Participants received aromatase inhibitors during adolescence.
• Reproductive function parameters were assessed in early adulthood.
• Literature review was conducted alongside the case series.
• No adverse effects on reproductive function were observed after treatment.
• Findings suggest long-term reproductive safety for individuals treated during adolescence.
• Larger prospective studies are recommended to confirm these findings.