Mn(II)-Catalyzed Switchable Synthesis of P(O)–C and P(O)–O Bonds from Alcohols and Diarylphosphine Oxides via Phospha-Brook Rearrangement

Key Points

• This research aims to develop a selective and efficient method for synthesizing P(O)–C and P(O)–O bonds using Mn(II) catalysis.
• Utilized Mn(II) as a catalyst for selective bond formation
• Employed alcohols and diarylphosphine oxides as starting materials
• Explored the Phospha–Brook rearrangement mechanism
• Successfully synthesized both P(O)–O and P(O)–C compounds
• Demonstrated a broad substrate scope for various alcohols
• Highlighted the biocompatibility and economic viability of the method.