Peptide Dendritic Polymerization-Enabled Stable and Tailorable Nanoparticles as Crosslinkers for Fabricating Multifunctional Hydrogels with Enhanced Wound Healing Efficacy

Key Points

• The aim is to develop stable and customizable nanoparticles for use in multifunctional hydrogels that improve wound healing.
• Utilized peptide dendritic polymerization to create nanoparticles
• Integrated nanoparticles as crosslinkers in hydrogel formulations
• Evaluated the structural stability and biocompatibility of the hydrogels
• The hydrogels exhibited enhanced mechanical stability
• Significantly improved wound healing outcomes in experimental models
• Demonstrated high biocompatibility with surrounding tissues