Clinical guidance and practical recommendations for probiotic use in patients with irritable bowel syndrome, functional constipation, and Clostridium difficile infection considering sex-based differences: a Korean translation

Key Points

• To provide clinical guidance and practical recommendations for probiotic use in digestive disorders, considering sex-based differences.
• Review of literature on probiotics for treating irritable bowel syndrome, functional constipation, and Clostridium difficile infection.
• Analysis of sex-based differences in response to probiotic treatment.
• Translation of clinical guidelines into Korean for wider accessibility.
• Probiotics show varying effects in treating irritable bowel syndrome and functional constipation based on sex.
• Guidelines were adapted to address sex-based differences in treatment outcomes for Clostridium difficile infection.
• Korean translation of recommendations enhances accessibility for practitioners.