This research aims to evaluate the protective effects of Commiphora leptophloeos extract on intestinal mucositis caused by 5-fluorouracil in mice.
Oral administration of a hydroethanolic extract of Commiphora leptophloeos to Swiss mice
Induction of intestinal mucositis using 5-fluorouracil
Assessment of mucin production in the duodenal segment
Commiphora leptophloeos extract significantly protected the duodenal mucosa from damage
Increased mucin production in treated mice compared to control
Demonstrated potential for mitigating chemotherapy-induced gut toxicity
Abstract
The oral administration of a hydroethanolic extract of CLF protected the duodenal segment of Swiss mice from 5-FU-induced intestinal mucositis, likely by increasing mucin production.