What question did this study set out to answer?

The aim is to sequence the genome of Streptomyces sp. MNU76 and characterize its biosynthetic potential.

April 17, 2026Open Access

Draft genome sequence of Streptomyces sp. MNU76, isolated from Indus River sediment, reveals uncharacterized biosynthetic gene clusters

AKAmrita KumariJawaharlal Nehru Technological University, Hyderabad GSGarima SunejaInstitute of Genomics and Integrative Biology SNSonam NainInstitute of Genomics and Integrative Biology

Key Points

The aim is to sequence the genome of Streptomyces sp. MNU76 and characterize its biosynthetic potential.
Isolated Streptomyces sp. MNU76 from river sediment.
Generated a draft genome comprising 37 contigs.
Analyzed GC content and identified biosynthetic gene clusters.
The genome is 10.5 Mb in size with 71% GC content.
Identified multiple predicted biosynthetic gene clusters.
Polyketide synthase pathways detected remain uncharacterized.

Abstract

Here, we present the draft genome sequence of Streptomyces sp. MNU76 isolated from river sediment. The genome comprises 37 contigs, 10.5 Mb in size, and 71% GC content. The species harbors multiple predicted biosynthetic gene clusters, including several polyketide synthase pathways; the natural products they encode remain uncharacterized.

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