A 48-year-old female developed critical de novo stenosis in a previously noncritical left main artery and significant in-stent restenosis 2 months after percutaneous coronary intervention.
Case Report (n=1)
48-year-old female of Middle Eastern descent with a recent history of coronary angioplasty presenting with acute coronary syndrome (ACS)
Percutaneous coronary intervention (PCI) with stenting
Development of critical stenosis in a previously noncritical segment (left main) and in-stent restenosissafety
This case highlights the rare complication of stent-induced de novo stenosis in previously noncritical segments, suggesting potential underlying hypersensitivity reactions.
ABSTRACT While percutaneous coronary interventions (PCI) with stenting are standard in treating coronary artery disease, rare complications such as stent‐induced de novo stenosis can paradoxically provoke acute coronary syndromes (ACS). We present the case of a 48‐year‐old female (Middle Eastern descent) with a recent history of coronary angioplasty, who presented with ACS 2 months post‐procedure. Coronary angiography revealed critical stenosis in the left main (LM), a previously noncritical segment. Additionally, there was significant in‐stent restenosis in the previously deployed stents in the left anterior descending (LAD) and left circumflex (LCX) arteries. This recurrent scenario of stenosis development in non‐stented regions following stent placement suggests the need to explore underlying hypersensitivity reactions as one of several possible mechanisms. Further investigation into the mechanisms, whether immunological or atherosclerotic, is warranted.
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Habibi et al. (Wed,) conducted a case report in Acute coronary syndrome / Stent-induced de novo stenosis (n=1). Percutaneous coronary intervention (PCI) with stenting was evaluated on Stent-induced de novo stenosis and in-stent restenosis. A 48-year-old female developed critical de novo stenosis in a previously noncritical left main artery and significant in-stent restenosis 2 months after percutaneous coronary intervention.
synapsesocial.com/papers/69e1cf985cdc762e9d8588d9 — DOI: https://doi.org/10.1002/ccr3.72555
Hamzeh Habibi
Iran University of Medical Sciences
Soroush Mostafavi
Iran University of Medical Sciences
Clinical Case Reports
Iran University of Medical Sciences
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