Betaine‐, xylitol‐, and extra virgin olive oil–based toothpaste modulates inflammation and oral nitric oxide pathway: Clinical trial in gingivitis

Key Points

• To evaluate the effects of a specialized toothpaste on inflammation and nitric oxide levels in gingivitis.
• Conducted a clinical trial in gingivitis patients
• Utilized toothpaste containing betaine, xylitol, and extra virgin olive oil
• Measured inflammation and nitric oxide-related markers as outcomes
• Toothpaste significantly reduced gum inflammation
• Improved markers related to nitric oxide production
• Participants experienced better oral health outcomes