To evaluate the safety and complication rates of combining neoadjuvant external beam radiotherapy (EBRT) with intraoperative radiotherapy (IORT) for patients with retroperitoneal sarcoma.
Conducted a clinical assessment of patients receiving neoadjuvant EBRT followed by IORT.
Analyzed complication rates post-surgery comparing combined therapy versus EBRT alone.
Monitored both low-grade and major complications.
Identified a frequent occurrence of low-grade complications.
Reported a 25% rate of major complications in the combined therapy group.
Findings indicate complication rates are similar to those observed with neoadjuvant EBRT alone.
Abstract
Neoadjuvant EBRT followed by resection with IORT is associated with frequent low-grade complications and a 25% rate of major complications, similar to neoadjuvant EBRT alone.