Plasma biomarkers and disease-modifying therapies for early Alzheimer's disease have created an urgent need for scalable care models. In this Perspectives, we describe how a health system is adapting dementia care delivery through a primary care provider (PCP)-centered initiative designed to improve diagnostic readiness and care capacity. The program integrates (1) blood-based biomarker testing into clinical workflows, (2) a Cognitive Assessment Visit (CAV) supported by Electronic Health Record-embedded decision tools, and (3) memory care co-management. Early implementation demonstrates that PCPs can be empowered to diagnose and manage cognitive impairment through structured workflows, targeted training, and specialist collaboration. In the first 26 weeks, 1,331 plasma p-tau217 tests were ordered by 104 clinicians, including 58 PCPs; 59 CAVs were completed by nine PCPs; and more than 330 asynchronous e-consults expanded specialist access. These results highlight the feasibility and challenges of integrating biomarker-informed dementia care within primary care workflows.
Burns et al. (Wed,) studied this question.