A 42-year-old female office worker presented with a three year history of persistent plaques affecting her left forehead, right cheek and right nasal sidewall. Examination revealed multiple discrete erythematous, brown, soft plaques affecting the patients face. The biopsy demonstrated severe diffuse active inflammation composed of lymphocytes, neutrophils, eosinophils and histiocytes. There was evidence of leukocytoclastic vasculitis and panniculitis. There was no evidence of inflammation in the upper dermis, no granulomas and no fungi identified.
Orr et al. (Tue,) studied this question.