The gut microbiome as an effector of metabolic disease gene variants

Key Points

• This study examines the relationship between the gut microbiome and genetic factors related to metabolic diseases.
• Reviewed existing literature on genetic drivers of the gut microbiome and metabolic disease.
• Analyzed studies linking gene variants to microbiome alterations and metabolic functions.
• Identified overlaps between genetic drivers of gut microbiome and metabolic disease.
• Suggests that genes influencing metabolism may do so by altering the gut microbiome.