Selective Turn-On Fluorescent Sensing of Endogenous Glutamate Using N-CQDs/Al Nanocomposites in Zebrafish CNS

Key Points

• To develop a sensitive method for detecting L-glutamate using N-CQDs/Al nanocomposites in zebrafish.
• Utilized N-doped carbon quantum dots (N-CQDs) and aluminum (Al) nanocomposites for sensor development.
• Performed in vivo experiments in zebrafish to evaluate fluorescence response to glutamate levels.
• Analyzed the fluorescent signal to determine glutamate concentration in the central nervous system.
• Successfully detected fluctuations in endogenous glutamate levels.
• Achieved real-time monitoring of neurotransmitter dynamics in live zebrafish.
• Demonstrated high sensitivity and specificity of the sensing mechanism.