Planar Rotor-Enabled Quenching-Resistant NIR-II Fluorophores for High-Contrast Bioimaging and Efficient Cancer Phototheranostics

Key Points

• The research aims to develop quenching-resistant NIR-II fluorophores with enhanced light harvesting for cancer applications.
• Synthesis of a novel acceptor-donor-acceptor fluorophore, BTP-2TCF
• Characterization of the photophysical properties of the fluorophore
• Evaluation of the fluorophore's performance in bioimaging and phototheranostic applications
• BTP-2TCF demonstrates strong light harvesting capabilities
• The fluorophore exhibits excellent photostability, minimizing quenching
• Enhanced contrast in bioimaging noted in cancer models