ATAD3A promotes bladder cancer progression by regulating glycolysis through MYC stabilization

Key Points

• This research aims to explore how ATAD3A influences bladder cancer progression through metabolic pathways.
• Analyzed the role of ATAD3A in bladder cancer progression.
• Investigated its interaction with USP10 and MYC.
• Assessed glycolytic regulation linked to ATAD3A.
• ATAD3A was found to promote the stabilization of MYC via USP10.
• Enhanced glycolytic reprogramming was observed in bladder cancer cells.
• The ATAD3A-USP10-MYC pathway is identified as a potential therapeutic target.