S1PR3 expression independently predicts the cumulative incidence of relapse in adult B-cell acute lymphoblastic leukemia: a single-center retrospective analysis

Key Points

• The research aims to determine if S1PR3 expression can independently predict relapse in adult B-cell acute lymphoblastic leukemia.
• Retrospective analysis of S1PR3 expression in adult B-ALL patients
• Assessment of cumulative incidence of relapse
• Evaluation of risk stratification based on biomarker levels
• Elevated S1PR3 expression correlates with higher relapse rates
• S1PR3 serves as an independent predictor beyond traditional factors
• Offers a potential target for new treatments.

Abstract