Polystyrene-Supported Aminobenzenesulfonic Acids as Bifunctional Heterogeneous Catalysts for the Synthesis of Isoxazoline Skeletons

Key Points

• The aim is to develop efficient synthetic methods for isoxazoline skeletons using bifunctional heterogeneous catalysts.
• Utilized polystyrene-supported aminobenzenesulfonic acids as catalysts.
• Explored 1,3-dipolar cycloaddition reactions for isoxazoline formation.
• Analyzed catalytic efficiency and reaction conditions.
• Achieved improved synthesis of isoxazolines with fewer steps.
• Demonstrated high catalytic activity of polystyrene-supported catalysts.
• Showed potential applications in pharmaceuticals and agrochemicals.