Synthesis of fluorene-indole/benzofuran bicyclic molecules through palladium-catalyzed carboheterofunctionalization of alkynes

Key Points

• The research aims to create a new approach for synthesizing fluorene–indole and fluorene–benzofuran compounds using palladium catalysts.
• Developed a palladium-catalyzed carboheterofunctionalization method.
• Utilized alkynes as starting materials.
• Examined yields of the resulting biscycles.
• Achieved moderate to good yields for fluorene–indole and fluorene–benzofuran structures.
• Demonstrated efficiency and broad applicability of the synthesis protocol.