Inhibition of Microglial TRPV1 Ameliorates Brain Injury After Intracerebral Hemorrhage by Suppressing AMPK / PINK1 ‐Mediated Mitophagy

Key Points

• This research focuses on the impact of inhibiting microglial TRPV1 on brain injury post-intracerebral hemorrhage.
• Inhibition of microglial TRPV1 in a model of intracerebral hemorrhage.
• Evaluation of inflammation and mitophagy changes after TRPV1 inhibition.
• Inhibition of TRPV1 reduces inflammation in the brain after injury.
• TRPV1 blockade positively affects mitophagy processes post-intracerebral hemorrhage.