Integration of a Screening-Guided Near-Infrared Aptasensor into a Portable Platform for Quantitative On-Site Detection of N¹-Methyladenosine

Key Points

• The aim is to develop a portable platform for the rapid and quantitative detection of N¹-methyladenosine (m¹A) modifications.
• Developed a near-infrared aptasensor for m¹A detection.
• Tested the aptasensor's performance in a portable device for on-site analysis.
• Employed screening-guided techniques to enhance sensitivity and specificity.
• Achieved rapid detection of m¹A with high accuracy.
• Demonstrated the aptasensor's effectiveness in various sample conditions.
• Showed potential for integration into field applications.