What question did this study set out to answer?

This research aims to investigate the relationship between insulin resistance surrogates and anemia in middle-aged and elderly individuals.

April 23, 2026Open Access

Association of four insulin resistance surrogates with anemia among middle-aged and elderly individuals: a cross-sectional study from the China Health and Retirement Longitudinal Study

Key Points

This research aims to investigate the relationship between insulin resistance surrogates and anemia in middle-aged and elderly individuals.
Cross-sectional analysis from the China Health and Retirement Longitudinal Study
Assessment of insulin resistance surrogates: TyG, TG/HDL-C, METS-IR, and eGDR
Population comprised middle-aged and elderly Chinese adults.
Higher TyG, TG/HDL-C, and METS-IR correlate with lower anemia rates.
Higher eGDR is associated with a higher prevalence of anemia.
Findings indicate complex metabolic-hematologic interactions.

Abstract

Higher levels of TyG, TG/HDL-C, and METS-IR are associated with lower prevalence of anemia, whereas higher eGDR is associated with higher anemia prevalence in middle-aged and elderly Chinese adults. These findings highlight complex metabolic-hematologic interactions, though the cross-sectional design precludes causal inference. Further longitudinal research is warranted to elucidate the underlying mechanisms.

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Cite This Study

Chen et al. (Mon,) studied this question.

synapsesocial.com/papers/69e9b6aa85696592c86eafca https://doi.org/https://doi.org/10.1186/s12889-026-27480-4

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