Overdoses of mefenamic acid, quetiapine, bupropion, venlafaxine and tramadol, respectively, were most commonly associated with seizures. Cefepime exhibited the highest seizure potential, in patients with impaired renal function. Tricyclic antidepressants (trimipramine, amitriptyline), tolperisone, mefenamic acid and bupropion were associated with seizures at relatively small overdoses compared to respective non-seizure cases.
Häuser et al. (Mon,) studied this question.