What question did this study set out to answer?

April 23, 2026Cochrane library1 citations

Buffered solutions versus 0.9% saline for resuscitation in critically ill adults and children

FMFrancisco de Paula Delgado Moya AAAlba Antequera AMAlfonso Muriel

Key Points

To compare the effectiveness of buffered solutions versus 0.9% saline for resuscitation in critically ill populations.
Conducted a systematic review updating a previous analysis from 2019.
Used registered protocol to ensure consistency and transparency in research design.
Buffered solutions may offer advantages in certain clinical outcomes compared to saline.
Findings support more modern approaches to fluid resuscitation in critically ill patients.

Abstract

This 2026 review is an update of the 2019 review. Both versions were conducted according to the published protocol. Protocol (2016) available at https://doi.org/10.1002/14651858.CD012247 The protocol was registered with PROSPERO (CRD42016045988). Original review (2019) available at https://doi.org/10.1002/14651858.CD012247.pub2.

اسأل الذكاء الاصطناعي

Bookmark

View Full Paper