What question did this study set out to answer?

This research aims to compare the diagnostic performance of IOTA Simple Rules between expert and nonexpert examiners.

April 23, 2026Journal of Clinical Ultrasound0 citations

Have Iota Simple Rules the Same Diagnostic Performance When Used by Nonexpert Examiners as Compared to Expert Examiners? Systematic Review and Meta‐Analisis

DHDominique HierardComplejo Asistencial Sótero del Río CPCarmen Padilla-PrietoHospital Universitari i Politècnic La Fe CAClaudia AregoHospital General Universitari de Castelló

Key Points

This research aims to compare the diagnostic performance of IOTA Simple Rules between expert and nonexpert examiners.
Conducted a systematic review and meta-analysis.
Evaluated the diagnostic accuracy of IOTA Simple Rules as performed by both expert and nonexpert operators.
Analyzed performance differences across various clinical experience levels.
IOTA Simple Rules show excellent diagnostic accuracy in both expert and nonexpert examiners.
Minor differences in performance between expert and nonexpert groups were observed.
The findings support the IOTA Simple Rules as a reliable tool for assessing adnexal masses.

Abstract

The IOTA Simple Rules demonstrate excellent diagnostic accuracy when used by both expert and nonexpert operators, with only minor differences in performance. These findings confirm that the Simple Rules are reproducible, robust and transferable across different clinical experience levels, supporting their role as an accessible and reliable triage tool for adnexal mass assessment, including outside tertiary referral centers.

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